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SubmiRine: assessing variants in microRNA targets using clinical genomic data sets
MicroRNAs (miRNAs) regulate gene expression by binding to partially complementary sequences on target mRNA transcripts, thereby causing their degradation, deadenylation, or inhibiting their translation. Genomic variants can alter miRNA regulation by modifying miRNA target sites, and multiple human d...
Autores principales: | Maxwell, Evan K., Campbell, Joshua D., Spira, Avrum, Baxevanis, Andreas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417167/ https://www.ncbi.nlm.nih.gov/pubmed/25813044 http://dx.doi.org/10.1093/nar/gkv256 |
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