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The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG methylation and histone H3/H4 binding

To effectively modulate the gene expression within an infected mammalian cell, the pathogen Mycobacterium tuberculosis would need to bring about epigenetic modifications at appropriate genomic loci. Working on this hypothesis, we show in this study that the mycobacterial protein Rv2966c is a 5-methy...

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Detalles Bibliográficos
Autores principales: Sharma, Garima, Upadhyay, Sandeep, Srilalitha, M., Nandicoori, Vinay K., Khosla, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417171/
https://www.ncbi.nlm.nih.gov/pubmed/25824946
http://dx.doi.org/10.1093/nar/gkv261