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RNA polymerase II pausing can be retained or acquired during activation of genes involved in the epithelial to mesenchymal transition

Promoter-proximal RNA polymerase II (Pol II) pausing is implicated in the regulation of gene transcription. However, the mechanisms of pausing including its dynamics during transcriptional responses remain to be fully understood. We performed global analysis of short capped RNAs and Pol II Chromatin...

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Detalles Bibliográficos
Autores principales: Samarakkody, Ann, Abbas, Ata, Scheidegger, Adam, Warns, Jessica, Nnoli, Oscar, Jokinen, Bradley, Zarns, Kris, Kubat, Brooke, Dhasarathy, Archana, Nechaev, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417172/
https://www.ncbi.nlm.nih.gov/pubmed/25820424
http://dx.doi.org/10.1093/nar/gkv263