RNA editing by T7 RNA polymerase bypasses InDel mutations causing unexpected phenotypic changes

DNA-dependent T7 RNA polymerase (T7 RNAP) is the most powerful tool for both gene expression and in vitro transcription. By using a Next Generation Sequencing (NGS) approach we have analyzed the polymorphism of a T7 RNAP-generated mRNA pool of the mboIIM2 gene. We find that the enzyme displays a rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Wons, Ewa, Furmanek-Blaszk, Beata, Sektas, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417176/
https://www.ncbi.nlm.nih.gov/pubmed/25824942
http://dx.doi.org/10.1093/nar/gkv269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417176/
https://www.ncbi.nlm.nih.gov/pubmed/25824942
http://dx.doi.org/10.1093/nar/gkv269

Ejemplares similares