A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation

MicroRNAs (miRNAs) have been implicated in DNA repair pathways through transcriptional responses to DNA damaging agents or through predicted miRNA regulation of DNA repair genes. We hypothesized that additional DNA damage regulating miRNAs could be identified by screening a library of 810 miRNA mime...

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Detalles Bibliográficos
Autores principales: Hatano, Koji, Kumar, Binod, Zhang, Yonggang, Coulter, Jonathan B., Hedayati, Mohammad, Mears, Brian, Ni, Xiaohua, Kudrolli, Tarana A., Chowdhury, Wasim H., Rodriguez, Ronald, DeWeese, Theodore L., Lupold, Shawn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417178/
https://www.ncbi.nlm.nih.gov/pubmed/25845598
http://dx.doi.org/10.1093/nar/gkv273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417178/
https://www.ncbi.nlm.nih.gov/pubmed/25845598
http://dx.doi.org/10.1093/nar/gkv273

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