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Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E(2) content in rat adjuvant-induced arthritis model
BACKGROUND: Arachidonic acid (ARA) is an essential fatty acid and a major constituent of biomembranes. It is converted into various lipid mediators, such as prostaglandin E(2) (PGE(2)), which is involved in the development of rheumatoid arthritis (RA). However, the effects of dietary ARA on RA are u...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417218/ https://www.ncbi.nlm.nih.gov/pubmed/25595700 http://dx.doi.org/10.1186/1476-511X-14-3 |