Phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences

BACKGROUND: Proline racemase (PRAC) enzymes of Trypanosoma cruzi (TcPRAC), the agent of Chagas disease, and Trypanosoma vivax (TvPRAC), the agent of livestock trypanosomosis, have been implicated in the B-cells polyclonal activation contributing to immunosuppression and the evasion of host defences....

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Detalles Bibliográficos
Autores principales: Caballero, Zuleima C, Costa-Martins, Andre G, Ferreira, Robson C, P Alves, João M, Serrano, Myrna G, Camargo, Erney P, Buck, Gregory A, Minoprio, Paola, G Teixeira, Marta M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417235/
https://www.ncbi.nlm.nih.gov/pubmed/25890302
http://dx.doi.org/10.1186/s13071-015-0829-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417235/
https://www.ncbi.nlm.nih.gov/pubmed/25890302
http://dx.doi.org/10.1186/s13071-015-0829-y

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