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miR-148b reverses cisplatin-resistance in non-small cell cancer cells via negatively regulating DNA (cytosine-5)-methyltransferase 1(DNMT1) expression

BACKGROUND: The emergence of drug resistance in cancer patients limits the success rate of clinical chemotherapy. MicroRNAs (miRNAs) may play a role in chemoresistance and may be involved in modulating of some drug resistance-related pathways in cancer cells. In this study, the involvement of microR...

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Detalles Bibliográficos
Autores principales: Sui, Chengguang, Meng, Fandong, Li, Yan, Jiang, Youhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417300/
https://www.ncbi.nlm.nih.gov/pubmed/25927928
http://dx.doi.org/10.1186/s12967-015-0488-y