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Mixture SNPs effect on phenotype in genome-wide association studies

BACKGROUND: Recently mixed linear models are used to address the issue of “missing" heritability in traditional Genome-wide association studies (GWAS). The models assume that all single-nucleotide polymorphisms (SNPs) are associated with the phenotypes of interest. However, it is more common th...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Shen, Haipeng, Liu, Hexuan, Guo, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417323/
https://www.ncbi.nlm.nih.gov/pubmed/25649116
http://dx.doi.org/10.1186/1471-2164-16-3