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Tetrandrine reverses drug resistance in isoniazid and ethambutol dual drug-resistant Mycobacterium tuberculosis clinical isolates

BACKGROUND: Tetrandrine is a natural chemical product purified from fourstamen stephania root which recently has been shown to act similarly as synthesized drug efflux pump inhibitor verapamil. The aim of the study is to examine whether tetrandrine could potentiate anti-tubercular drugs to which Myc...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Yan, Jie, Xu, Kaijin, Ji, Zhongkang, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417324/
https://www.ncbi.nlm.nih.gov/pubmed/25887373
http://dx.doi.org/10.1186/s12879-015-0905-0