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Evolving concepts of tumor heterogeneity

Past and recent findings on tumor heterogeneity have led clinicians and researchers to broadly define cancer development as an evolving process. This evolutionary model of tumorigenesis has largely been shaped by seminal reports of fitness-promoting mutations conferring a malignant cellular phenotyp...

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Detalles Bibliográficos
Autores principales: Zellmer, Victoria R, Zhang, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417538/
https://www.ncbi.nlm.nih.gov/pubmed/25937891
http://dx.doi.org/10.1186/2045-3701-4-69