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Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB

Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. Thus, the generation of Ag-specific IgG in response to infection or immunization has the potential to downmodulate immune prote...

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Detalles Bibliográficos
Autores principales: Franz, Brian J., Li, Ying, Bitsaktsis, Constantine, Iglesias, Bibiana V., Pham, Giang, Sunagar, Raju, Kumar, Sudeep, Gosselin, Edmund J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417568/
https://www.ncbi.nlm.nih.gov/pubmed/25961064
http://dx.doi.org/10.1155/2015/840842