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1,25-Dihydroxyvitamin D(3) Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPARγ Signaling Pathway

Macrophages, especially their activation state, are closely related to the progression of diabetic nephropathy. Classically activated macrophages (M1) are proinflammatory effectors, while alternatively activated macrophages (M2) exhibit anti-inflammatory properties. 1,25-Dihydroxyvitamin D(3) has re...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoliang, Zhou, Min, Guo, Yinfeng, Song, Zhixia, Liu, Bicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417570/
https://www.ncbi.nlm.nih.gov/pubmed/25961000
http://dx.doi.org/10.1155/2015/157834