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High Order Gene-Gene Interactions in Eight Single Nucleotide Polymorphisms of Renin-Angiotensin System Genes for Hypertension Association Study

Several single nucleotide polymorphisms (SNPs) of renin-angiotensin system (RAS) genes are associated with hypertension (HT) but most of them are focusing on single locus effects. Here, we introduce an unbalanced function based on multifactor dimensionality reduction (MDR) for multiloci genotypes to...

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Detalles Bibliográficos
Autores principales: Yang, Cheng-Hong, Lin, Yu-Da, Wu, Shyh-Jong, Chuang, Li-Yeh, Chang, Hsueh-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417588/
https://www.ncbi.nlm.nih.gov/pubmed/25961019
http://dx.doi.org/10.1155/2015/454091