Punicalagin Induces Nrf2/HO-1 Expression via Upregulation of PI3K/AKT Pathway and Inhibits LPS-Induced Oxidative Stress in RAW264.7 Macrophages

Reactive oxygen species (ROS) and oxidative stress are thought to play a central role in potentiating macrophage activation, causing excessive inflammation, tissue damage, and sepsis. Recently, we have shown that punicalagin (PUN) exhibits anti-inflammatory activity in LPS-stimulated macrophages. Ho...

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Detalles Bibliográficos
Autores principales: Xu, Xiaolong, Li, Hongquan, Hou, Xiaolin, Li, Deyin, He, Shasha, Wan, Changrong, Yin, Peng, Liu, Mingjiang, Liu, Fenghua, Xu, Jianqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417599/
https://www.ncbi.nlm.nih.gov/pubmed/25969626
http://dx.doi.org/10.1155/2015/380218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417599/
https://www.ncbi.nlm.nih.gov/pubmed/25969626
http://dx.doi.org/10.1155/2015/380218

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