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Punicalagin Induces Nrf2/HO-1 Expression via Upregulation of PI3K/AKT Pathway and Inhibits LPS-Induced Oxidative Stress in RAW264.7 Macrophages

Reactive oxygen species (ROS) and oxidative stress are thought to play a central role in potentiating macrophage activation, causing excessive inflammation, tissue damage, and sepsis. Recently, we have shown that punicalagin (PUN) exhibits anti-inflammatory activity in LPS-stimulated macrophages. Ho...

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Detalles Bibliográficos
Autores principales:	Xu, Xiaolong, Li, Hongquan, Hou, Xiaolin, Li, Deyin, He, Shasha, Wan, Changrong, Yin, Peng, Liu, Mingjiang, Liu, Fenghua, Xu, Jianqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417599/ https://www.ncbi.nlm.nih.gov/pubmed/25969626 http://dx.doi.org/10.1155/2015/380218

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