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Binding Studies on Isolated Porcine Small Intestinal Mucosa and in vitro Toxicity Studies Reveal Lack of Effect of C. perfringens Beta-Toxin on the Porcine Intestinal Epithelium

Beta-toxin (CPB) is the essential virulence factor of C. perfringens type C causing necrotizing enteritis (NE) in different hosts. Using a pig infection model, we showed that CPB targets small intestinal endothelial cells. Its effect on the porcine intestinal epithelium, however, could not be adequa...

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Detalles Bibliográficos
Autores principales: Roos, Simone, Wyder, Marianne, Candi, Ahmet, Regenscheit, Nadine, Nathues, Christina, van Immerseel, Filip, Posthaus, Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417965/
https://www.ncbi.nlm.nih.gov/pubmed/25860161
http://dx.doi.org/10.3390/toxins7041235