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The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases
The danger model was proposed by Polly Matzinger as complement to the traditional self-non-self- (SNS-) model to explain the immunoreactivity. The danger model proposes a central role of the tissular cells' discomfort as an element to prime the immune response processes in opposition to the tra...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417989/ https://www.ncbi.nlm.nih.gov/pubmed/25973436 http://dx.doi.org/10.1155/2015/506089 |