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The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases

The danger model was proposed by Polly Matzinger as complement to the traditional self-non-self- (SNS-) model to explain the immunoreactivity. The danger model proposes a central role of the tissular cells' discomfort as an element to prime the immune response processes in opposition to the tra...

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Detalles Bibliográficos
Autores principales: Pacheco-Tena, César, González-Chávez, Susana Aideé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417989/
https://www.ncbi.nlm.nih.gov/pubmed/25973436
http://dx.doi.org/10.1155/2015/506089