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Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive neurodegeneration. Pathogenetic mechanisms, triggered by β-amyloid (Aβ) accumulation, include oxidative stress, derived from energy homeostasis deregulation and involving mitochondria and peroxisomes. We...

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Detalles Bibliográficos
Autores principales: Porcellotti, Sara, Fanelli, Francesca, Fracassi, Anna, Sepe, Sara, Cecconi, Francesco, Bernardi, Cinzia, Cimini, AnnaMaria, Cerù, Maria Paola, Moreno, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418010/
https://www.ncbi.nlm.nih.gov/pubmed/25973140
http://dx.doi.org/10.1155/2015/967203