The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2

It is currently accepted that superoxide anion (O(2) (•−)) is an important mediator in pain and inflammation. The role of superoxide anion in pain and inflammation has been mainly determined indirectly by modulating its production and inactivation. Direct evidence using potassium superoxide (KO(2)),...

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Detalles Bibliográficos
Autores principales: Maioli, N.A., Zarpelon, A.C., Mizokami, S.S., Calixto-Campos, C., Guazelli, C.F.S., Hohmann, M.S.N., Pinho-Ribeiro, F.A., Carvalho, T.T., Manchope, M.F., Ferraz, C.R., Casagrande, R., Verri, W.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2015
Materias:
Biomedical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418362/
https://www.ncbi.nlm.nih.gov/pubmed/25714890
http://dx.doi.org/10.1590/1414-431X20144187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418362/
https://www.ncbi.nlm.nih.gov/pubmed/25714890
http://dx.doi.org/10.1590/1414-431X20144187

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