Cargando…

The Common Chymotrypsinogen C (CTRC) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population

OBJECTIVES: Recurrent acute pancreatitis (RAP) is a complex inflammatory disorder that may progress to fibrosis and other irreversible features recognized as chronic pancreatitis (CP). Chymotrypsinogen C (CTRC) protects the pancreas by degrading prematurely activated trypsinogen. Rare mutations are...

Descripción completa

Detalles Bibliográficos
Autores principales: LaRusch, Jessica, Lozano-Leon, Antonio, Stello, Kimberly, Moore, Amanda, Muddana, Venkata, O'Connell, Michael, Diergaarde, Brenda, Yadav, Dhiraj, Whitcomb, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418406/
https://www.ncbi.nlm.nih.gov/pubmed/25569187
http://dx.doi.org/10.1038/ctg.2014.13