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Strategies to Rescue the Consequences of Inducible Arginase-1 Deficiency in Mice
Arginase-1 catalyzes the conversion of arginine to ornithine and urea, which is the final step of the urea cycle used to remove excess ammonia from the body. Arginase-1 deficiency leads to hyperargininemia in mice and man with severe lethal consequences in the former and progressive neurological imp...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418594/ https://www.ncbi.nlm.nih.gov/pubmed/25938595 http://dx.doi.org/10.1371/journal.pone.0125967 |