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Strategies to Rescue the Consequences of Inducible Arginase-1 Deficiency in Mice

Arginase-1 catalyzes the conversion of arginine to ornithine and urea, which is the final step of the urea cycle used to remove excess ammonia from the body. Arginase-1 deficiency leads to hyperargininemia in mice and man with severe lethal consequences in the former and progressive neurological imp...

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Detalles Bibliográficos
Autores principales:	Ballantyne, Laurel L., Sin, Yuan Yan, St. Amand, Tim, Si, Joshua, Goossens, Steven, Haenebalcke, Lieven, Haigh, Jody J., Kyriakopoulou, Lianna, Schulze, Andreas, Funk, Colin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418594/ https://www.ncbi.nlm.nih.gov/pubmed/25938595 http://dx.doi.org/10.1371/journal.pone.0125967

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