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Cyclization of the Urokinase Receptor-Derived Ser-Arg-Ser-Arg-Tyr Peptide Generates a Potent Inhibitor of Trans-Endothelial Migration of Monocytes

The receptor for the urokinase-type plasminogen activator (uPAR) is a widely recognized master regulator of cell migration and uPAR(88-92) is the minimal sequence required to induce cell motility. We and others have previously documented that the uPAR(88-92) sequence, even in the form of synthetic l...

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Detalles Bibliográficos
Autores principales: Yousif, Ali Munaim, Minopoli, Michele, Bifulco, Katia, Ingangi, Vincenzo, Di Carluccio, Gioconda, Merlino, Francesco, Motti, Maria Letizia, Grieco, Paolo, Carriero, Maria Vincenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418665/
https://www.ncbi.nlm.nih.gov/pubmed/25938482
http://dx.doi.org/10.1371/journal.pone.0126172