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Cyclization of the Urokinase Receptor-Derived Ser-Arg-Ser-Arg-Tyr Peptide Generates a Potent Inhibitor of Trans-Endothelial Migration of Monocytes
The receptor for the urokinase-type plasminogen activator (uPAR) is a widely recognized master regulator of cell migration and uPAR(88-92) is the minimal sequence required to induce cell motility. We and others have previously documented that the uPAR(88-92) sequence, even in the form of synthetic l...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418665/ https://www.ncbi.nlm.nih.gov/pubmed/25938482 http://dx.doi.org/10.1371/journal.pone.0126172 |