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Regulation of Hepatocyte Growth Factor in Mice with Pneumonia by Peptidases and Trans-Alveolar Flux

Hepatocyte growth factor (HGF) promotes lung epithelial repair after injury. Because prior studies established that human neutrophil proteases inactivate HGF in vitro, we predicted that HGF levels decrease in lungs infiltrated with neutrophils and that injury is less severe in lungs lacking HGF-inac...

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Detalles Bibliográficos
Autores principales: Raymond, Wilfred W., Xu, Xiang, Nimishakavi, Shilpa, Le, Catherine, McDonald, Donald M., Caughey, George H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418689/
https://www.ncbi.nlm.nih.gov/pubmed/25938594
http://dx.doi.org/10.1371/journal.pone.0125797