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Regulation of Hepatocyte Growth Factor in Mice with Pneumonia by Peptidases and Trans-Alveolar Flux
Hepatocyte growth factor (HGF) promotes lung epithelial repair after injury. Because prior studies established that human neutrophil proteases inactivate HGF in vitro, we predicted that HGF levels decrease in lungs infiltrated with neutrophils and that injury is less severe in lungs lacking HGF-inac...
Autores principales: | Raymond, Wilfred W., Xu, Xiang, Nimishakavi, Shilpa, Le, Catherine, McDonald, Donald M., Caughey, George H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418689/ https://www.ncbi.nlm.nih.gov/pubmed/25938594 http://dx.doi.org/10.1371/journal.pone.0125797 |
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