Functional Validation of Rare Human Genetic Variants Involved in Homologous Recombination Using Saccharomyces cerevisiae

Systems for the repair of DNA double-strand breaks (DSBs) are necessary to maintain genome integrity and normal functionality of cells in all organisms. Homologous recombination (HR) plays an important role in repairing accidental and programmed DSBs in mitotic and meiotic cells, respectively. Failu...

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Detalles Bibliográficos
Autores principales: Lee, Min-Soo, Yu, Mi, Kim, Kyoung-Yeon, Park, Geun-Hee, Kwack, KyuBum, Kim, Keun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418691/
https://www.ncbi.nlm.nih.gov/pubmed/25938495
http://dx.doi.org/10.1371/journal.pone.0124152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418691/
https://www.ncbi.nlm.nih.gov/pubmed/25938495
http://dx.doi.org/10.1371/journal.pone.0124152

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