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Crystal Structure of Fad35R from Mycobacterium tuberculosis H37Rv in the Apo-State

Fad35R from Mycobacterium tuberculosis binds to the promoter site of Fad35 operon and its DNA binding activities are reduced in the presence of tetracycline and palmitoyl-CoA. We resolved the crystal structure of Fad35R using single-wavelength anomalous diffraction method (SAD). Fad35R comprises can...

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Detalles Bibliográficos
Autores principales: Singh, Appu Kumar, Manjasetty, Babu, GL, Balasubramani, Koul, Sukirte, Kaushik, Abhishek, Ekka, Mary Krishna, Singh, Vijay, Kumaran, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418694/
https://www.ncbi.nlm.nih.gov/pubmed/25938298
http://dx.doi.org/10.1371/journal.pone.0124333