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Predicting Peptide-Mediated Interactions on a Genome-Wide Scale

We describe a method to predict protein-protein interactions (PPIs) formed between structured domains and short peptide motifs. We take an integrative approach based on consensus patterns of known motifs in databases, structures of domain-motif complexes from the PDB and various sources of non-struc...

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Detalles Bibliográficos
Autores principales: Chen, T. Scott, Petrey, Donald, Garzon, Jose Ignacio, Honig, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418708/
https://www.ncbi.nlm.nih.gov/pubmed/25938916
http://dx.doi.org/10.1371/journal.pcbi.1004248