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Predicting Peptide-Mediated Interactions on a Genome-Wide Scale
We describe a method to predict protein-protein interactions (PPIs) formed between structured domains and short peptide motifs. We take an integrative approach based on consensus patterns of known motifs in databases, structures of domain-motif complexes from the PDB and various sources of non-struc...
Autores principales: | Chen, T. Scott, Petrey, Donald, Garzon, Jose Ignacio, Honig, Barry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418708/ https://www.ncbi.nlm.nih.gov/pubmed/25938916 http://dx.doi.org/10.1371/journal.pcbi.1004248 |
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