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Prevalence of Thymine—Adenine Dinucleotide Repeat, IL28B and IFNL4 in Thai Population and Correlation with Spontaneous Clearance and Treatment Outcome of Hepatitis C Infection

BACKGROUND: The interleukin-28B (IL28B) gene polymorphism is a strong baseline predictor of sustained virological response (SVR) in hepatitis C virus (HCV) treatment. The length of thymine—adenine dinucleotide repeats, or (TA)(n), in the regulatory region of IL28B can affect interferon transcription...

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Detalles Bibliográficos
Autores principales: Thong, Vo Duy, Wasitthankasem, Rujipat, Tangkijvanich, Pisit, Vongpunsawad, Sompong, Poovorawan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418711/
https://www.ncbi.nlm.nih.gov/pubmed/25938236
http://dx.doi.org/10.1371/journal.pone.0125400