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In Vitro and In Vivo Evaluations of PLGA Microspheres Containing Nalmefene
Poor patient compliance, untoward reactions and unstable blood drug levels after the bolus administration are impeding the pharmacotherapy for insobriety. A long-acting preparation may address these limitations. The aim of this paper was to further investigate the in vitro characteristics and in viv...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418713/ https://www.ncbi.nlm.nih.gov/pubmed/25938514 http://dx.doi.org/10.1371/journal.pone.0125953 |