Cargando…

In Vitro and In Vivo Evaluations of PLGA Microspheres Containing Nalmefene

Poor patient compliance, untoward reactions and unstable blood drug levels after the bolus administration are impeding the pharmacotherapy for insobriety. A long-acting preparation may address these limitations. The aim of this paper was to further investigate the in vitro characteristics and in viv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Xiangyang, Lin, Wen, Xing, Chuanfeng, Yang, Yanfang, Chi, Qiang, Zhang, Hui, Li, Ying, Li, Zhiping, Yang, Yang, Yang, Zhenbo, Li, Mingyuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418713/ https://www.ncbi.nlm.nih.gov/pubmed/25938514 http://dx.doi.org/10.1371/journal.pone.0125953

Ejemplares similares

Controlled Release of Dutasteride from Biodegradable Microspheres: In Vitro and In Vivo Studies
por: Xie, Xiangyang, et al.
Publicado: (2014)

Preparation and in vivo/in vitro characterization of Ticagrelor PLGA sustained-release microspheres for injection
por: Hao, Linkun, et al.
Publicado: (2021)

Preparation and in vitro/in vivo evaluation of PLGA microspheres containing norquetiapine for long-acting injection
por: Park, Chun-Woong, et al.
Publicado: (2018)

Development of a novel morphological paclitaxel-loaded PLGA microspheres for effective cancer therapy: in vitro and in vivo evaluations
por: Zhang, Zongrui, et al.
Publicado: (2018)

Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release
por: Dong, Ni, et al.
Publicado: (2020)

Preparation, Characterization and in vitro/in vivo Evaluation of Lovastatin-Loaded PLGA Microspheres by Local Administration for Femoral Head Necrosis
por: Sun, Yang, et al.
Publicado: (2021)

Preparation and Release Profiles in Vitro/Vivo of Galantamine Pamoate Loaded Poly (Lactideco-Glycolide) (PLGA) Microspheres
por: Du, Liping, et al.
Publicado: (2021)

Intra-articular injection PLGA blends sustained-release microspheres loaded with meloxicam: preparation, optimization, evaluation in vitro and in vivo
por: Sun, Zheng, et al.
Publicado: (2022)

Preparation of PLGA Nanoparticles by Milling Spongelike PLGA Microspheres
por: Lee, Jimin, et al.
Publicado: (2022)

Preparation, Characterization, In Vitro Release and Degradation of Cathelicidin-BF-30-PLGA Microspheres
por: Li, Lili, et al.
Publicado: (2014)

Development of Risperidone PLGA Microspheres
por: D'Souza, Susan, et al.
Publicado: (2014)

The effects of different amounts of drug microspheres on the vivo and vitro performance of the PLGA/β-TCP scaffold
por: Lin, Liulan, et al.
Publicado: (2016)

The Effect of Polymer Blends on the In Vitro Release/Degradation and Pharmacokinetics of Moxidectin-Loaded PLGA Microspheres
por: Zhang, Hongjuan, et al.
Publicado: (2023)

Cartilage Extracellular Matrix Scaffold With Kartogenin-Encapsulated PLGA Microspheres for Cartilage Regeneration
por: Zhao, Yanhong, et al.
Publicado: (2020)

Inhalable Nano-Dimpled Microspheres Containing Budesonide-PLGA for Improved Aerodynamic Performance
por: Han, Chang-Soo, et al.
Publicado: (2022)

Insulin-loaded PLGA microspheres for glucose-responsive release
por: Wu, Jun-Zi, et al.
Publicado: (2017)

Protein Loading into Spongelike PLGA Microspheres
por: Kim, Yuyoung, et al.
Publicado: (2021)

PLGA Microspheres Incorporated Gelatin Scaffold: Microspheres Modulate Scaffold Properties
por: Banerjee, Indranil, et al.
Publicado: (2009)

Rifapentine-linezolid-loaded PLGA microspheres for interventional therapy of cavitary pulmonary tuberculosis: preparation and in vitro characterization
por: Huang, Jieyun, et al.
Publicado: (2017)

Paclitaxel-loaded PLGA microspheres with a novel morphology to facilitate drug delivery and antitumor efficiency
por: Zhang, Zongrui, et al.
Publicado: (2018)

Process analytical technology as in-process control tool in semi-continuous manufacturing of PLGA/PEG-PLGA microspheres
por: Anwar, Arfidin, et al.
Publicado: (2023)

Nalmefene: a new approach to the treatment of alcohol dependence
por: Paille, François, et al.
Publicado: (2014)

Stereoselectivity evaluation of chiral chitosan microspheres delivery system containing rac-KET in vitro and in vivo
por: Yin, Li-Na, et al.
Publicado: (2019)

Formulation and In Vitro Evaluation of Alendronate Sodium/PLGA Microspheres for Applications in Bone Related Disorders
por: DECA, A.G., et al.
Publicado: (2015)

Heuristic modeling of macromolecule release from PLGA microspheres
por: Szlęk, Jakub, et al.
Publicado: (2013)

PLGA sustained-release microspheres loaded with an insoluble small-molecule drug: microfluidic-based preparation, optimization, characterization, and evaluation in vitro and in vivo
por: Su, Yue, et al.
Publicado: (2022)

Nalmefene: a new approach to the treatment of alcohol dependence [Corrigendum]
Publicado: (2015)

Evaluation in alcohol use disorders – insights from the nalmefene experience
por: Naudet, Florian, et al.
Publicado: (2016)

The antimicrobial effects of PLGA microspheres containing the antimicrobial peptide OP-145 on clinically isolated pathogens in bone infections
por: Cheng, Ye, et al.
Publicado: (2022)

Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles
por: Fodor-Kardos, Andrea, et al.
Publicado: (2020)

Drug-nanoencapsulated PLGA microspheres prepared by emulsion electrospray with controlled release behavior
por: Yao, Shenglian, et al.
Publicado: (2016)

PEGylated apoptotic protein-loaded PLGA microspheres for cancer therapy
por: Byeon, Hyeong Jun, et al.
Publicado: (2015)

Immunogenicity of pulsatile-release PLGA microspheres for single-injection vaccination
por: Guarecuco, Rohiverth, et al.
Publicado: (2018)

Assessment of Residual Solvent and Drug in PLGA Microspheres by Derivative Thermogravimetry
por: Shim, Hyunjin, et al.
Publicado: (2020)

Patient preferences and perspectives regarding reducing alcohol consumption: role of nalmefene
por: Luquiens, Amandine, et al.
Publicado: (2014)

Drinking Levels and Profiles of Alcohol Addicted Rats Predict Response to Nalmefene
por: Foo, Jerome Clifford, et al.
Publicado: (2019)

Long‐term safety and efficacy of nalmefene in Japanese patients with alcohol dependence
por: Higuchi, Susumu, et al.
Publicado: (2020)

Characterization, Stability and Biological Activity In Vitro of Cathelicidin-BF-30 Loaded 4-Arm Star-Shaped PEG-PLGA Microspheres
por: Bao, Yueli, et al.
Publicado: (2018)

Effects of HepaSphere microsphere encapsule epirubicin with a new loading method transarterial chemoembolization: in vitro and in vivo experiments
por: Zhang, Wen, et al.
Publicado: (2023)

Release of PLGA–encapsulated dexamethasone from microsphere loaded porous surfaces
por: Dawes, G. J. S., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_venqg5csl8ig4aovga40lncu8a