HYS-32-Induced Microtubule Catastrophes in Rat Astrocytes Involves the PI3K-GSK3beta Signaling Pathway

HYS-32 is a novel derivative of combretastatin-A4 (CA-4) previously shown to induce microtubule coiling in rat primary astrocytes. In this study, we further investigated the signaling mechanism and EB1, a microtubule-associated end binding protein, involved in HYS-32-induced microtubule catastrophes...

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Detalles Bibliográficos
Autores principales: Chiu, Chi-Ting, Liao, Chih-Kai, Shen, Chien-Chang, Tang, Tswen-Kei, Jow, Guey-Mei, Wang, Hwai-Shi, Wu, Jiahn-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418738/
https://www.ncbi.nlm.nih.gov/pubmed/25938237
http://dx.doi.org/10.1371/journal.pone.0126217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418738/
https://www.ncbi.nlm.nih.gov/pubmed/25938237
http://dx.doi.org/10.1371/journal.pone.0126217

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