Cruzipain Activates Latent TGF-β from Host Cells during T. cruzi Invasion

Several studies indicate that the activity of cruzipain, the main lysosomal cysteine peptidase of Trypanosoma cruzi, contributes to parasite infectivity. In addition, the parasitic invasion process of mammalian host cells is described to be dependent on the activation of the host TGF-β signaling pat...

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Detalles Bibliográficos
Autores principales: Ferrão, Patrícia Mello, d'Avila-Levy, Claudia Masini, Araujo-Jorge, Tania Cremonini, Degrave, Wim Maurits, Gonçalves, Antônio da Silva, Garzoni, Luciana Ribeiro, Lima, Ana Paula, Feige, Jean Jacques, Bailly, Sabine, Mendonça-Lima, Leila, Waghabi, Mariana Caldas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418758/
https://www.ncbi.nlm.nih.gov/pubmed/25938232
http://dx.doi.org/10.1371/journal.pone.0124832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418758/
https://www.ncbi.nlm.nih.gov/pubmed/25938232
http://dx.doi.org/10.1371/journal.pone.0124832

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