The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors

The murine Cebpa gene contains an evolutionarily conserved 453 bp enhancer located at +37 kb that, together with its promoter, directs expression to myeloid progenitors and to long-term hematopoietic stem cells in transgenic mice. In human acute myeloid leukemia cases, the enhancer lacks point mutat...

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Detalles Bibliográficos
Autores principales: Cooper, Stacy, Guo, Hong, Friedman, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418761/
https://www.ncbi.nlm.nih.gov/pubmed/25938608
http://dx.doi.org/10.1371/journal.pone.0126385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418761/
https://www.ncbi.nlm.nih.gov/pubmed/25938608
http://dx.doi.org/10.1371/journal.pone.0126385

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