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Comparative Evaluation of Sloppy Molecular Beacon and Dual-Labeled Probe Melting Temperature Assays to Identify Mutations in Mycobacterium tuberculosis Resulting in Rifampin, Fluoroquinolone and Aminoglycoside Resistance

Several molecular assays to detect resistance to Rifampin, the Fluoroquinolones, and Aminoglycosides in Mycobacterium tuberculosis (M. tuberculosis) have been recently described. A systematic approach for comparing these assays in the laboratory is needed in order to determine the relative advantage...

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Detalles Bibliográficos
Autores principales: Roh, Sandy S., Smith, Laura E., Lee, Jong Seok, Via, Laura E., Barry, Clifton E., Alland, David, Chakravorty, Soumitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418795/
https://www.ncbi.nlm.nih.gov/pubmed/25938476
http://dx.doi.org/10.1371/journal.pone.0126257