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Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease Function

The eukaryotic Meiotic Recombination protein 11 (Mre11) plays pivotal roles in the DNA damage response (DDR). Specifically, Mre11 senses and signals DNA double strand breaks (DSB) and facilitates their repair through effector proteins belonging to either homologous recombination (HR) or non-homologo...

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Detalles Bibliográficos
Autores principales: Badugu, Sugith Babu, Nabi, Shaik Abdul, Vaidyam, Pratap, Laskar, Shyamasree, Bhattacharyya, Sunanda, Bhattacharyya, Mrinal Kanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418825/
https://www.ncbi.nlm.nih.gov/pubmed/25938776
http://dx.doi.org/10.1371/journal.pone.0125358