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Crosstalk between the Unfolded Protein Response and NF-κB-Mediated Inflammation in the Progression of Chronic Kidney Disease

The chronic inflammatory response is emerging as an important therapeutic target in progressive chronic kidney disease. A key transcription factor in the induction of chronic inflammation is NF-κB. Recent studies have demonstrated that sustained activation of the unfolded protein response (UPR) can...

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Detalles Bibliográficos
Autores principales: Mohammed-Ali, Zahraa, Cruz, Gaile L., Dickhout, Jeffrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419235/
https://www.ncbi.nlm.nih.gov/pubmed/25977931
http://dx.doi.org/10.1155/2015/428508