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Hierarchical differentiation competence in response to retinoic acid ensures stem cell maintenance during mouse spermatogenesis

Stem cells ensure tissue homeostasis through the production of differentiating and self-renewing progeny. In some tissues, this is achieved by the function of a definitive stem cell niche. However, the mechanisms that operate in mouse spermatogenesis are unknown because undifferentiated spermatogoni...

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Detalles Bibliográficos
Autores principales: Ikami, Kanako, Tokue, Moe, Sugimoto, Ryo, Noda, Chiyo, Kobayashi, Satoru, Hara, Kenshiro, Yoshida, Shosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419276/
https://www.ncbi.nlm.nih.gov/pubmed/25858458
http://dx.doi.org/10.1242/dev.118695