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Hierarchical differentiation competence in response to retinoic acid ensures stem cell maintenance during mouse spermatogenesis
Stem cells ensure tissue homeostasis through the production of differentiating and self-renewing progeny. In some tissues, this is achieved by the function of a definitive stem cell niche. However, the mechanisms that operate in mouse spermatogenesis are unknown because undifferentiated spermatogoni...
Autores principales: | Ikami, Kanako, Tokue, Moe, Sugimoto, Ryo, Noda, Chiyo, Kobayashi, Satoru, Hara, Kenshiro, Yoshida, Shosei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419276/ https://www.ncbi.nlm.nih.gov/pubmed/25858458 http://dx.doi.org/10.1242/dev.118695 |
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