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Alveolar macrophage–derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes

Type I interferons (IFNs) are important for host defense from viral infections, acting to restrict viral production in infected cells and to promote antiviral immune responses. However, the type I IFN system has also been associated with severe lung inflammatory disease in response to respiratory sy...

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Detalles Bibliográficos
Autores principales: Goritzka, Michelle, Makris, Spyridon, Kausar, Fahima, Durant, Lydia R., Pereira, Catherine, Kumagai, Yutaro, Culley, Fiona J., Mack, Matthias, Akira, Shizuo, Johansson, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419339/
https://www.ncbi.nlm.nih.gov/pubmed/25897172
http://dx.doi.org/10.1084/jem.20140825