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Alveolar macrophage–derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes
Type I interferons (IFNs) are important for host defense from viral infections, acting to restrict viral production in infected cells and to promote antiviral immune responses. However, the type I IFN system has also been associated with severe lung inflammatory disease in response to respiratory sy...
Autores principales: | Goritzka, Michelle, Makris, Spyridon, Kausar, Fahima, Durant, Lydia R., Pereira, Catherine, Kumagai, Yutaro, Culley, Fiona J., Mack, Matthias, Akira, Shizuo, Johansson, Cecilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419339/ https://www.ncbi.nlm.nih.gov/pubmed/25897172 http://dx.doi.org/10.1084/jem.20140825 |
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