Cargando…

The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector differentiation

Invariant natural killer T cells (iNKT cells) are innate-like T cells that rapidly produce cytokines that impact antimicrobial immune responses, asthma, and autoimmunity. These cells acquire multiple effector fates during their thymic development that parallel those of CD4(+) T helper cells. The num...

Descripción completa

Detalles Bibliográficos
Autores principales: Carr, Tiffany, Krishnamoorthy, Veena, Yu, Shuyang, Xue, Hai-Hui, Kee, Barbara L., Verykokakis, Mihalis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419352/
https://www.ncbi.nlm.nih.gov/pubmed/25897173
http://dx.doi.org/10.1084/jem.20141849