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Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer’s disease mouse model

INTRODUCTION: Recent studies have shown that several strains of transgenic Alzheimer’s disease (AD) mice overexpressing the amyloid precursor protein (APP) have cortical hyperexcitability, and their results have suggested that this aberrant network activity may be a mechanism by which amyloid-β (Aβ)...

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Detalles Bibliográficos
Autores principales: Nygaard, Haakon B, Kaufman, Adam C, Sekine-Konno, Tomoko, Huh, Linda L, Going, Hilary, Feldman, Samantha J, Kostylev, Mikhail A, Strittmatter, Stephen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419386/
https://www.ncbi.nlm.nih.gov/pubmed/25945128
http://dx.doi.org/10.1186/s13195-015-0110-9