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Glucose 6-phosphate dehydrogenase knockdown enhances IL-8 expression in HepG2 cells via oxidative stress and NF-κB signaling pathway

BACKGROUND: This study was designed to investigate the effect of glucose 6-phosphate dehydrogenase (G6PD) deficiency on pro-inflammatory cytokine secretion using a palmitate-induced inflammation HepG2 in vitro model. The modulation of cellular pro-inflammatory cytokine expression under G6PD deficien...

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Detalles Bibliográficos
Autores principales: Yang, Hung-Chi, Cheng, Mei-Ling, Hua, Yi-Syuan, Wu, Yi-Hsuan, Lin, Hsin-Ru, Liu, Hui-Ya, Ho, Hung-Yao, Chiu, Daniel Tsun-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419400/
https://www.ncbi.nlm.nih.gov/pubmed/25945076
http://dx.doi.org/10.1186/s12950-015-0078-z