Cargando…

Glucose 6-phosphate dehydrogenase knockdown enhances IL-8 expression in HepG2 cells via oxidative stress and NF-κB signaling pathway

BACKGROUND: This study was designed to investigate the effect of glucose 6-phosphate dehydrogenase (G6PD) deficiency on pro-inflammatory cytokine secretion using a palmitate-induced inflammation HepG2 in vitro model. The modulation of cellular pro-inflammatory cytokine expression under G6PD deficien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Hung-Chi, Cheng, Mei-Ling, Hua, Yi-Syuan, Wu, Yi-Hsuan, Lin, Hsin-Ru, Liu, Hui-Ya, Ho, Hung-Yao, Chiu, Daniel Tsun-Yee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419400/ https://www.ncbi.nlm.nih.gov/pubmed/25945076 http://dx.doi.org/10.1186/s12950-015-0078-z

Ejemplares similares

Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB Signaling
por: Wu, Yi-Hsuan, et al.
Publicado: (2015)

Knockdown of nucleophosmin induces S-phase arrest in HepG2 cells
por: Wang, Qing-Qing, et al.
Publicado: (2011)

Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts
por: Wu, Yi-Hsuan, et al.
Publicado: (2009)

Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis
por: Wu, Yi-Hsuan, et al.
Publicado: (2018)

Glucose-6-Phosphate Dehydrogenase, Redox Homeostasis and Embryogenesis
por: Chen, Po-Hsiang, et al.
Publicado: (2022)

MCU-knockdown attenuates high glucose-induced inflammation through regulating MAPKs/NF-κB pathways and ROS production in HepG2 cells
por: Panahi, Ghodratollah, et al.
Publicado: (2018)

Dysregulation of gene expression in ABCC6 knockdown HepG2 cells
por: Miglionico, Rocchina, et al.
Publicado: (2014)

DNMT1/PKR double knockdowned HepG2 (HepG2-DP) cells have high hepatic function and differentiation ability
por: Tanaka-yachi, Rieko, et al.
Publicado: (2022)

Clitocine Reversal of P-Glycoprotein Associated Multi-Drug Resistance through Down-Regulation of Transcription Factor NF-κB in R-HepG2 Cell Line
por: Sun, Jianguo, et al.
Publicado: (2012)

Induction of Apoptosis by Berberine in Hepatocellular Carcinoma HepG2 Cells via Downregulation of NF-κB
por: Li, Min, et al.
Publicado: (2017)

Diminished COX-2/PGE(2)-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells
por: Lin, Hsin-Ru, et al.
Publicado: (2016)

Impaired embryonic development in glucose-6-phosphate dehydrogenase-deficient Caenorhabditis elegans due to abnormal redox homeostasis induced activation of calcium-independent phospholipase and alteration of glycerophospholipid metabolism
por: Chen, Tzu-Ling, et al.
Publicado: (2017)

Anti-Inflammatory Effect of Protopine through MAPK and NF-κB Signaling Regulation in HepG2 Cell
por: Kim, MinGyu, et al.
Publicado: (2022)

Knockdown of astrocyte elevated gene-1 inhibits growth through suppression of IL-6 secretion in HepG2 human hepatoma cells
por: DENG, HUAN, et al.
Publicado: (2014)

Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells
por: Tian, Yu-Syuan, et al.
Publicado: (2018)

Benzophenones from Anemarrhena asphodeloides Bge. Exhibit Anticancer Activity in HepG2 Cells via the NF-κB Signaling Pathway
por: Wu, De-Ling, et al.
Publicado: (2019)

Knockdown of autophagy-related gene LC3 enhances the sensitivity of HepG(2) cells to epirubicin
por: PENG, WANXIN, et al.
Publicado: (2015)

ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype
por: Miglionico, Rocchina, et al.
Publicado: (2017)

Inhibition of NF-κB transcriptional activation in HepG2 cells by diterpenoids from the soft coral Sinularia maxima
por: Thao, Nguyen Phuong, et al.
Publicado: (2013)

TKTL1 Knockdown Impairs Hypoxia-Induced Glucose-6-phosphate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase Overexpression
por: Baptista, Inês, et al.
Publicado: (2022)

Curdlan sulphate modulates protein synthesis and enhances NF-κB and C/EBP binding activity in HepG2 cells
por: Guzdek, A., et al.
Publicado: (1997)

Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF-κB signaling
por: Ma, Baitao, et al.
Publicado: (2021)

Knockdown of Decoy Receptor 3 Impairs Growth and Invasiveness of Hepatocellular Carcinoma Cell Line of HepG2
por: Zhou, Xiao-Na, et al.
Publicado: (2016)

Inhibitory Effect of Styrylpyrone Extract of Phellinus linteus on Hepatic Steatosis in HepG2 Cells
por: Chiu, Chun-Hung, et al.
Publicado: (2023)

tert-Butyl Hydroperoxide (tBHP)-Induced Lipid Peroxidation and Embryonic Defects Resemble Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in C. elegans
por: Yang, Hung-Chi, et al.
Publicado: (2020)

Geniposide promotes autophagy to inhibit insulin resistance in HepG2 cells via P62/NF-κB/GLUT-4
por: Jiang, Hongwei, et al.
Publicado: (2017)

Separation and Identification of Resveratrol Butyrate Ester Complexes and Their Bioactivity in HepG2 Cell Models
por: Shih, Ming-Kuei, et al.
Publicado: (2021)

Matrix Metalloproteinase 2 Knockdown Suppresses the Proliferation of HepG2 and Huh7 Cells and Enhances the Cisplatin Effect
por: Liu, Jiangwei, et al.
Publicado: (2019)

Nicotinamide Phosphoribosyltransferase Knockdown Leads to Lipid Accumulation in HepG2 Cells through The SIRT1-AMPK Pathway
por: Ilbeigi, Davod, et al.
Publicado: (2020)

Effective Inhibition of Xenografts of Hepatocellular Carcinoma (HepG2) by Rapamycin and Bevacizumab in an Intrahepatic Model
por: Ong, Lai-Chun, et al.
Publicado: (2009)

2,4,6-Trinitrotoluene Induces Apoptosis via ROS-Regulated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in HepG2 and Hep3B Cells
por: Liao, Hung-Yu, et al.
Publicado: (2017)

Poor Prognosis in Nasopharyngeal Cancer Patients with Low Glucose‐6‐phosphate‐dehydrogenase Activity
por: Cheng, Ann‐Joy, et al.
Publicado: (2001)

Oleanolic Acid Attenuates Insulin Resistance via NF-κB to Regulate the IRS1-GLUT4 Pathway in HepG2 Cells
por: Li, Ming, et al.
Publicado: (2015)

Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells
por: Chen, Hung-Chen, et al.
Publicado: (2016)

Inhibition of TNF-α-Mediated NF-κB Transcriptional Activity by Dammarane-Type Ginsenosides from Steamed Flower Buds of Panax ginseng in HepG2 and SK-Hep1 Cells
por: Cho, Kyoungwon, et al.
Publicado: (2014)

Intracellular distribution pattern of procalcitonin in human monocytes and HepG2 cells
por: Ruβwurm, S, et al.
Publicado: (1999)

Inhibition of TNF-α-mediated NF-κB Transcriptional Activity in HepG2 Cells by Dammarane-type Saponins from Panax ginseng Leaves
por: Song, Seok Bean, et al.
Publicado: (2012)

Ginsenoside Rg1 Ameliorates Palmitic Acid-Induced Hepatic Steatosis and Inflammation in HepG2 Cells via the AMPK/NF-κB Pathway
por: Xiao, Qing, et al.
Publicado: (2019)

Comparison of the Impact of Xanthohumol and Phenethyl Isothiocyanate and Their Combination on Nrf2 and NF-κB Pathways in HepG2 Cells In Vitro and Tumor Burden In Vivo
por: Cykowiak, Marta, et al.
Publicado: (2021)

The Cholesterol-Modulating Effect of Methanol Extract of Pigeon Pea (Cajanus cajan (L.) Millsp.) Leaves on Regulating LDLR and PCSK9 Expression in HepG2 Cells
por: Chang, Heng-Yuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kc9g7f6l5522hdgbqj15kf98af