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Transcriptional profiling of PRKG2-null growth plate identifies putative down-stream targets of PRKG2

BACKGROUND: Kinase activity of cGMP-dependent, type II, protein kinase (PRKG2) is required for the proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function in rodent and bovine models results in dwarfism. The objective of this stu...

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Detalles Bibliográficos
Autores principales:	Koltes, James E, Kumar, Dinesh, Kataria, Ranjit S, Cooper, Vickie, Reecy, James M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419418/ https://www.ncbi.nlm.nih.gov/pubmed/25924610 http://dx.doi.org/10.1186/s13104-015-1136-6

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