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A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain

BACKGROUND: There is a critical need for proven drugs other than non-steroidal anti-inflammatory drugs for treatment of degenerative joint disease (DJD) pain in dogs. Antibodies against nerve growth factor (NGF) are analgesic in rodent models and in humans with DJD. This pilot study aimed to evaluat...

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Detalles Bibliográficos
Autores principales: Lascelles, B Duncan X, Knazovicky, David, Case, Beth, Freire, Mila, Innes, John F, Drew, Alexander C, Gearing, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419463/
https://www.ncbi.nlm.nih.gov/pubmed/25926287
http://dx.doi.org/10.1186/s12917-015-0413-x