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Tunable translational control using site-specific unnatural amino acid incorporation in Escherichia coli

Translation of target gene transcripts in Escherichia coli harboring UAG amber stop codons can be switched on by the amber-codon-specific incorporation of an exogenously supplied unnatural amino acid, 3-iodo-(L)-tyrosine. Here, we report that this translational switch can control the translational e...

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Detalles Bibliográficos
Autor principal: Kato, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419535/
https://www.ncbi.nlm.nih.gov/pubmed/25945307
http://dx.doi.org/10.7717/peerj.904